Gonococcal surveillance in Thailand

  • Antimicrobial resistance markers as a monitoring index of gonorrhoea in Thailand

    Multiplex PCR was applied to explore the antimicrobial-resistance profiles of 145 gonococci isolated from Bangrak Hospital, Thailand in 2007. All isolates were clearly identified for the plasmid-mediated resistant types of penicillin (Asia, Africa and Toronto) and tetracycline(American and Dutch). This method can also predict the decreased susceptibility to ciprofloxacin by detection of Ser-91 mutation. Prevalence rates of penicillinase-producing Neisseria gonorrhoeae (PPNG) and high-level tetracycline-resistance

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  • One-step PCR for the identification of multiple antimicrobial resistance in Neisseria gonorrhoeae

    A significant increase in multiple resistance of Neisseria gonorrhoeae toward penicillin, tetracycline and fluoroquinolones has been reported worldwide (Gerbase et al., 1998; Knapp et al., 1997). The need to identify and characterize the resistance profile of N. gonorrhoeae has been recognized as a public health priority. This has been addressed by World Health Organization (WHO) in their establishment of surveillance programs for monitoring the resistance of N. gonorrhoeae to penicillin, tetracycline and ciprofloxacin. In Thailand, plasmid-mediated resistance to penicillin and tetracycline is commonly found among N. gonorrhoeae isolates. Of the six types of β-lactamase producing plasmids (Asia, Africa, Toronto, Rio, Nimes and New Zeal

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  • Antibiograms and randomly amplified polymorphic DNA-polymerase chain reactions (RAPD-PCR) as epidemiological markers of gonorrhea

    The need to identify and characterize the resistance profile of N. gonorrhoeae has been recognized as a public health priority. This has been addressed by World Health Organization (WHO) in their establishment of surveillance programs for monitoring the resistance of N. gonorrhoeae to penicillin, tetracycline and ciprofloxacin. In Thailand, plasmid-mediated resistance to penicillin and tetracycline is commonly found among N. gonorrhoeae isolates. Of the six types of β-lactamase producing plasmids

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  • Anal_pap_smear

    The focal group in this topic is men who have sex with men (MSM). Why is this group important? Well, the total population of Thailand is around 65 million. The male population is about 32 million and among all of the males, MSM is found in around 3 percent of the population which is approximately 960,000. Since 1989, the MSM group has had a higher rate of HIV infection (Fig1) and the prediction of future infections from Asian epidemic model project will be even higher than the other risk groups which are those of sex workers and IV drug users (Fig2).

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